E643-1142 Screening compound: 3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[4,5-b]pyridine

E643-1142 Screening compound: 3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[4,5-b]pyridine
E643-1142 Screening compound: 3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[4,5-b]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound E643-1142
3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[4,5-b]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E643-1142

Molecular Formula

C21H15F4N3S (C21 H15 F4 N3 S)

Compound Name

3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[4,5-b]pyridine

IUPAC name

3-[(3-fluorophenyl)methyl]-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)-3H-imidazo[45-b]pyridine

SMILES

FC(c1cccc(CSc(n2Cc3cc(F)ccc3)nc3c2nccc3)c1)(F)F

InChI

InChI=1S/C21H15F4N3S/c22-17-7-2-4-14(11-17)12-28-19-18(8-3-9-26-19)27-20(28)29-13-15-5-1-6-16(10-15)21(23,24)25/h1-11H,12-13H2

InChI Key

GUKLSBFCVVKYPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14907191

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.685

Distribution Coefficient, logD

5.684

Water Solubility, LogSw

-6.24

Polar Surface Area

20.384

Acid Dissociation Constant (pKa)

18.89

Base Dissociation Constant (pKb)

4.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

E643-1142 in Drug Discovery

Included in Screening Libraries

Antibacterial Compounds Library (13827 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with E643-1142 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E643-1142?
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What is the minimum amount of E643-1142 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E643-1142
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E643-1142
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E643-1142 available by request