E643-2005 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide

E643-2005 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide
E643-2005 Screening compound: 2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E643-2005
2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E643-2005

Molecular Formula

C16H16N4O2S (C16 H16 N4 O2 S)

Compound Name

2-{3H-imidazo[4,5-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide

IUPAC name

2-{3H-imidazo[45-b]pyridin-2-ylsulfanyl}-N-(2-methoxy-5-methylphenyl)acetamide

SMILES

Cc(cc1)cc(NC(CSc([nH]2)nc3c2nccc3)=O)c1OC

InChI

InChI=1S/C16H16N4O2S/c1-10-5-6-13(22-2)12(8-10)18-14(21)9-23-16-19-11-4-3-7-17-15(11)20-16/h3-8H,9H2,1-2H3,(H,18,21)(H,17,19,20)

InChI Key

FTJKSTQCYDEUCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05700898

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

328.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.812

Distribution Coefficient, logD

1.804

Water Solubility, LogSw

-2.43

Polar Surface Area

58.436

Acid Dissociation Constant (pKa)

9.16

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.80

E643-2005 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E643-2005 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E643-2005?
Check Price and Availability of E643-2005, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E643-2005 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E643-2005
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E643-2005
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E643-2005 available by request