E647-0150 Screening compound: N-cyclohexyl-2-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetamide

E647-0150 Screening compound: N-cyclohexyl-2-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetamide
E647-0150 Screening compound: N-cyclohexyl-2-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E647-0150
N-cyclohexyl-2-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E647-0150

Molecular Formula

C18H24N2O2 (C18 H24 N2 O2)

Compound Name

N-cyclohexyl-2-(2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)acetamide

IUPAC name

N-cyclohexyl-2-(2-oxo-2345-tetrahydro-1H-1-benzazepin-1-yl)acetamide

SMILES

O=C(CN(c1c(CCC2)cccc1)C2=O)NC1CCCCC1

InChI

InChI=1S/C18H24N2O2/c21-17(19-15-9-2-1-3-10-15)13-20-16-11-5-4-7-14(16)8-6-12-18(20)22/h4-5,7,11,15H,1-3,6,8-10,12-13H2,(H,19,21)

InChI Key

RBHXFAOOSGKBCC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27600896

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

300.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.390

Distribution Coefficient, logD

3.390

Water Solubility, LogSw

-3.65

Polar Surface Area

40.147

Acid Dissociation Constant (pKa)

15.47

Base Dissociation Constant (pKb)

4.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

E647-0150 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Nervous system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with E647-0150 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E647-0150?
Check Price and Availability of E647-0150, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E647-0150 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E647-0150
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E647-0150
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E647-0150 available by request