E667-0223 Screening compound: N~6~-(3-methyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamide

E667-0223 Screening compound: N~6~-(3-methyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamide
E667-0223 Screening compound: N~6~-(3-methyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E667-0223
N~6~-(3-methyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E667-0223

Molecular Formula

C18H19N3O2S (C18 H19 N3 O2 S)

Compound Name

N~6~-(3-methyl-2-pyridyl)-2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamide

IUPAC name

n/a

SMILES

Cc1cccnc1NS(c(cc1)cc2c1[nH]c1c2CCCC1)(=O)=O

InChI

InChI=1S/C18H19N3O2S/c1-12-5-4-10-19-18(12)21-24(22,23)13-8-9-17-15(11-13)14-6-2-3-7-16(14)20-17/h4-5,8-11,20H,2-3,6-7H2,1H3,(H,19,21)

InChI Key

JCGFQGGVTYKWRJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14908886

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.182

Distribution Coefficient, logD

2.153

Water Solubility, LogSw

-3.35

Polar Surface Area

61.346

Acid Dissociation Constant (pKa)

6.41

Base Dissociation Constant (pKb)

1.72

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

E667-0223 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E667-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E667-0223?
Check Price and Availability of E667-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E667-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E667-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E667-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E667-0223 available by request