E667-0272 Screening compound: 6-[(3-methylpiperidin-1-yl)sulfonyl]-2,3,4,9-tetrahydro-1H-carbazole

E667-0272 Screening compound: 6-[(3-methylpiperidin-1-yl)sulfonyl]-2,3,4,9-tetrahydro-1H-carbazole
E667-0272 Screening compound: 6-[(3-methylpiperidin-1-yl)sulfonyl]-2,3,4,9-tetrahydro-1H-carbazole alternative view

Chemical Structure Depiction of ChemDiv screening compound E667-0272
6-[(3-methylpiperidin-1-yl)sulfonyl]-2,3,4,9-tetrahydro-1H-carbazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E667-0272

Molecular Formula

C18H24N2O2S (C18 H24 N2 O2 S)

Compound Name

6-[(3-methylpiperidin-1-yl)sulfonyl]-2,3,4,9-tetrahydro-1H-carbazole

IUPAC name

6-[(3-methylpiperidin-1-yl)sulfonyl]-2349-tetrahydro-1H-carbazole

SMILES

CC(CCC1)CN1S(c(cc1)cc2c1[nH]c1c2CCCC1)(=O)=O

InChI

InChI=1S/C18H24N2O2S/c1-13-5-4-10-20(12-13)23(21,22)14-8-9-18-16(11-14)15-6-2-3-7-17(15)19-18/h8-9,11,13,19H,2-7,10,12H2,1H3/t13-/m0/s1

InChI Key

IPIHGFQZZHDFIH-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD14908915

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

332.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.402

Distribution Coefficient, logD

3.402

Water Solubility, LogSw

-3.93

Polar Surface Area

42.653

Acid Dissociation Constant (pKa)

18.51

Base Dissociation Constant (pKb)

-3.35

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

55.60

E667-0272 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS targets activity set (6557 compounds)

Protein-Protein Interaction Library (218420 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Nervous system
Targets:
  • Ion Channels
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E667-0272 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E667-0272?
Check Price and Availability of E667-0272, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E667-0272 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E667-0272
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E667-0272
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E667-0272 available by request