E667-2168 Screening compound: N-(4-bromo-3-methylphenyl)-2-(N-methyl2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamido)acetamide

E667-2168 Screening compound: N-(4-bromo-3-methylphenyl)-2-(N-methyl2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamido)acetamide
E667-2168 Screening compound: N-(4-bromo-3-methylphenyl)-2-(N-methyl2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamido)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E667-2168
N-(4-bromo-3-methylphenyl)-2-(N-methyl2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamido)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E667-2168

Molecular Formula

C22H24BrN3O3S (C22 H24 BrN3 O3 S)

Compound Name

N-(4-bromo-3-methylphenyl)-2-(N-methyl2,3,4,9-tetrahydro-1H-carbazole-6-sulfonamido)acetamide

IUPAC name

N-(4-bromo-3-methylphenyl)-2-(N-methyl2349-tetrahydro-1H-carbazole-6-sulfonamido)acetamide

SMILES

Cc(cc(cc1)NC(CN(C)S(c(cc2)cc3c2[nH]c2c3CCCC2)(=O)=O)=O)c1Br

InChI

InChI=1S/C22H24BrN3O3S/c1-14-11-15(7-9-19(14)23)24-22(27)13-26(2)30(28,29)16-8-10-21-18(12-16)17-5-3-4-6-20(17)25-21/h7-12,25H,3-6,13H2,1-2H3,(H,24,27)

InChI Key

XRHXDIWGDWUUGX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14909266

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.618

Distribution Coefficient, logD

4.617

Water Solubility, LogSw

-4.37

Polar Surface Area

66.723

Acid Dissociation Constant (pKa)

10.21

Base Dissociation Constant (pKb)

-1.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

E667-2168 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Endocrine

References: we are preparing a list of scientific research reports with E667-2168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E667-2168?
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What is the minimum amount of E667-2168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E667-2168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E667-2168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E667-2168 available by request