E676-1183 Screening compound: 5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-1,3-benzothiazol-2-yl)thiophene-2-carboxamide

E676-1183 Screening compound: 5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-1,3-benzothiazol-2-yl)thiophene-2-carboxamide
E676-1183 Screening compound: 5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-1,3-benzothiazol-2-yl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E676-1183
5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-1,3-benzothiazol-2-yl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E676-1183

Molecular Formula

C18H20BrN3O2S2 (C18 H20 BrN3 O2 S2)

Compound Name

5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-1,3-benzothiazol-2-yl)thiophene-2-carboxamide

IUPAC name

5-bromo-N-[2-(dimethylamino)ethyl]-N-(4-ethoxy-13-benzothiazol-2-yl)thiophene-2-carboxamide

SMILES

CCOc1cccc2c1nc(N(CCN(C)C)C(c(s1)ccc1Br)=O)s2

InChI

InChI=1S/C18H20BrN3O2S2/c1-4-24-12-6-5-7-13-16(12)20-18(26-13)22(11-10-21(2)3)17(23)14-8-9-15(19)25-14/h5-9H,4,10-11H2,1-3H3

InChI Key

YUMMLVBUDZSUTI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11984862

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

454.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.000

Distribution Coefficient, logD

4.592

Water Solubility, LogSw

-4.49

Polar Surface Area

38.240

Acid Dissociation Constant (pKa)

23.37

Base Dissociation Constant (pKb)

7.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E676-1183 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Dark Chemical Matter Library (18430 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Structure:
  • Pool
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E676-1183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E676-1183?
Check Price and Availability of E676-1183, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E676-1183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E676-1183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E676-1183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E676-1183 available by request