E676-2321 Screening compound: N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide

E676-2321 Screening compound: N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide
E676-2321 Screening compound: N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E676-2321
N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E676-2321

Molecular Formula

C18H21N3O2S (C18 H21 N3 O2 S)

Compound Name

N-(5,7-dimethyl-1,3-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide

IUPAC name

N-(57-dimethyl-13-benzothiazol-2-yl)-N-[2-(dimethylamino)ethyl]furan-2-carboxamide

SMILES

Cc1cc(C)c2sc(N(CCN(C)C)C(c3ccco3)=O)nc2c1

InChI

InChI=1S/C18H21N3O2S/c1-12-10-13(2)16-14(11-12)19-18(24-16)21(8-7-20(3)4)17(22)15-6-5-9-23-15/h5-6,9-11H,7-8H2,1-4H3

InChI Key

MWXMNUAHZVROBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14022541

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

343.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.165

Distribution Coefficient, logD

3.752

Water Solubility, LogSw

-4.15

Polar Surface Area

37.819

Acid Dissociation Constant (pKa)

23.76

Base Dissociation Constant (pKb)

7.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E676-2321 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

Antibacterial Compounds Library (13827 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Immune system
  • animal
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E676-2321 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E676-2321?
Check Price and Availability of E676-2321, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E676-2321 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E676-2321
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E676-2321
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E676-2321 available by request