E677-1326 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)-3-phenoxypropanamide

E677-1326 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)-3-phenoxypropanamide
E677-1326 Screening compound: N-[3-(dimethylamino)propyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)-3-phenoxypropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E677-1326
N-[3-(dimethylamino)propyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)-3-phenoxypropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E677-1326

Molecular Formula

C21H24FN3O2S (C21 H24 FN3 O2 S)

Compound Name

N-[3-(dimethylamino)propyl]-N-(4-fluoro-1,3-benzothiazol-2-yl)-3-phenoxypropanamide

IUPAC name

N-[3-(dimethylamino)propyl]-N-(4-fluoro-13-benzothiazol-2-yl)-3-phenoxypropanamide

SMILES

CN(C)CCCN(C(CCOc1ccccc1)=O)c1nc(c(F)ccc2)c2s1

InChI

InChI=1S/C21H24FN3O2S/c1-24(2)13-7-14-25(19(26)12-15-27-16-8-4-3-5-9-16)21-23-20-17(22)10-6-11-18(20)28-21/h3-6,8-11H,7,12-15H2,1-2H3

InChI Key

SEZYVGIGHFGETN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11985799

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

401.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.349

Distribution Coefficient, logD

2.143

Water Solubility, LogSw

-4.23

Polar Surface Area

36.901

Acid Dissociation Constant (pKa)

23.29

Base Dissociation Constant (pKb)

9.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E677-1326 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

CNS BBB Library (22607 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E677-1326 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E677-1326?
Check Price and Availability of E677-1326, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E677-1326 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E677-1326
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E677-1326
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E677-1326 available by request