E681-0243 Screening compound: 5-(4-chlorobenzenesulfonamido)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyridine-3-carboxamide

E681-0243 Screening compound: 5-(4-chlorobenzenesulfonamido)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyridine-3-carboxamide
E681-0243 Screening compound: 5-(4-chlorobenzenesulfonamido)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E681-0243
5-(4-chlorobenzenesulfonamido)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E681-0243

Molecular Formula

C20H16ClN3O5S (C20 H16 ClN3 O5 S)

Compound Name

5-(4-chlorobenzenesulfonamido)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)pyridine-3-carboxamide

IUPAC name

5-(4-chlorobenzenesulfonamido)-N-(23-dihydro-14-benzodioxin-6-yl)pyridine-3-carboxamide

SMILES

O=C(c1cc(NS(c(cc2)ccc2Cl)(=O)=O)cnc1)Nc(cc1)cc2c1OCCO2

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.88

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.765

Distribution Coefficient, logD

2.192

Water Solubility, LogSw

-3.69

Polar Surface Area

89.410

Acid Dissociation Constant (pKa)

6.96

Base Dissociation Constant (pKb)

3.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

E681-0243 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E681-0243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E681-0243?
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What is the minimum amount of E681-0243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E681-0243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E681-0243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E681-0243 available by request