E681-1375 Screening compound: 4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide

E681-1375 Screening compound: 4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide
E681-1375 Screening compound: 4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E681-1375
4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E681-1375

Molecular Formula

C25H28N4O5S (C25 H28 N4 O5 S)

Compound Name

4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide

IUPAC name

4-methoxy-N-{2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]pyridin-4-yl}-N-methylbenzene-1-sulfonamide

SMILES

CN(c1cc(C(N(CC2)CCN2c(cc2)ccc2OC)=O)ncc1)S(c(cc1)ccc1OC)(=O)=O

InChI

InChI=1S/C25H28N4O5S/c1-27(35(31,32)23-10-8-22(34-3)9-11-23)20-12-13-26-24(18-20)25(30)29-16-14-28(15-17-29)19-4-6-21(33-2)7-5-19/h4-13,18H,14-17H2,1-3H3

InChI Key

GIHZVMCOYUGEDO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14909678

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.536

Distribution Coefficient, logD

3.535

Water Solubility, LogSw

-3.85

Polar Surface Area

77.104

Acid Dissociation Constant (pKa)

27.67

Base Dissociation Constant (pKb)

4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

E681-1375 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E681-1375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E681-1375?
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What is the minimum amount of E681-1375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E681-1375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E681-1375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E681-1375 available by request