E683-0136 Screening compound: 4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide

E683-0136 Screening compound: 4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide
E683-0136 Screening compound: 4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E683-0136
4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E683-0136

Molecular Formula

C24H17F4N3O (C24 H17 F4 N3 O)

Compound Name

4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide

IUPAC name

4-fluoro-N-(4-methyl-2-{[3-(trifluoromethyl)phenyl]amino}quinolin-6-yl)benzamide

SMILES

Cc1c(cc(cc2)NC(c(cc3)ccc3F)=O)c2nc(Nc2cc(C(F)(F)F)ccc2)c1

InChI

InChI=1S/C24H17F4N3O/c1-14-11-22(29-18-4-2-3-16(12-18)24(26,27)28)31-21-10-9-19(13-20(14)21)30-23(32)15-5-7-17(25)8-6-15/h2-13H,1H3,(H,29,31)(H,30,32)

InChI Key

UQKVDVIGPVTLGE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14909750

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.880

Distribution Coefficient, logD

6.864

Water Solubility, LogSw

-5.93

Polar Surface Area

41.140

Acid Dissociation Constant (pKa)

8.92

Base Dissociation Constant (pKb)

5.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

E683-0136 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E683-0136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E683-0136?
Check Price and Availability of E683-0136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E683-0136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E683-0136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E683-0136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E683-0136 available by request