E683-0251 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide

E683-0251 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide
E683-0251 Screening compound: N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E683-0251
N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E683-0251

Molecular Formula

C23H17ClFN3O (C23 H17 ClFN3 O)

Compound Name

N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide

IUPAC name

N-{2-[(3-chlorophenyl)amino]-4-methylquinolin-6-yl}-4-fluorobenzamide

SMILES

Cc(c1c2)cc(Nc3cccc(Cl)c3)nc1ccc2NC(c(cc1)ccc1F)=O

InChI

InChI=1S/C23H17ClFN3O/c1-14-11-22(26-18-4-2-3-16(24)12-18)28-21-10-9-19(13-20(14)21)27-23(29)15-5-7-17(25)8-6-15/h2-13H,1H3,(H,26,28)(H,27,29)

InChI Key

SECWKPUFVAEPEY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14909809

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.86

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.591

Distribution Coefficient, logD

6.577

Water Solubility, LogSw

-6.40

Polar Surface Area

41.140

Acid Dissociation Constant (pKa)

8.92

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

E683-0251 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E683-0251 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E683-0251?
Check Price and Availability of E683-0251, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E683-0251 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E683-0251
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E683-0251
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E683-0251 available by request