E715-0989 Screening compound: 1-{6H,7H,8H,9H-pyrido[2,1-h]purin-4-yl}-1,2,3,4-tetrahydroquinoline

E715-0989 Screening compound: 1-{6H,7H,8H,9H-pyrido[2,1-h]purin-4-yl}-1,2,3,4-tetrahydroquinoline
E715-0989 Screening compound: 1-{6H,7H,8H,9H-pyrido[2,1-h]purin-4-yl}-1,2,3,4-tetrahydroquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound E715-0989
1-{6H,7H,8H,9H-pyrido[2,1-h]purin-4-yl}-1,2,3,4-tetrahydroquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E715-0989

Molecular Formula

C18H19N5 (C18 H19 N5)

Compound Name

1-{6H,7H,8H,9H-pyrido[2,1-h]purin-4-yl}-1,2,3,4-tetrahydroquinoline

IUPAC name

1-{6H7H8H9H-pyrido[21-h]purin-4-yl}-1234-tetrahydroquinoline

SMILES

C(CCn12)Cc2nc2c1ncnc2N(CCC1)c2c1cccc2

InChI

InChI=1S/C18H19N5/c1-2-8-14-13(6-1)7-5-11-22(14)17-16-18(20-12-19-17)23-10-4-3-9-15(23)21-16/h1-2,6,8,12H,3-5,7,9-11H2

InChI Key

DZPKJVFWJXIBGI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14911864

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

305.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

1.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.420

Distribution Coefficient, logD

3.419

Water Solubility, LogSw

-3.46

Polar Surface Area

34.929

Acid Dissociation Constant (pKa)

18.55

Base Dissociation Constant (pKb)

4.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

E715-0989 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with E715-0989 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E715-0989?
Check Price and Availability of E715-0989, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E715-0989 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E715-0989
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E715-0989
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E715-0989 available by request