E734-0137 Screening compound: N-(3-fluoro-4-methylphenyl)-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

E734-0137 Screening compound: N-(3-fluoro-4-methylphenyl)-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide
E734-0137 Screening compound: N-(3-fluoro-4-methylphenyl)-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-0137
N-(3-fluoro-4-methylphenyl)-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-0137

Molecular Formula

C16H14FN3O4S (C16 H14 FN3 O4 S)

Compound Name

N-(3-fluoro-4-methylphenyl)-7-methyl-2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

IUPAC name

N-(3-fluoro-4-methylphenyl)-7-methyl-23-dioxo-1234-tetrahydroquinoxaline-6-sulfonamide

SMILES

Cc(ccc(NS(c(cc1NC2=O)c(C)cc1NC2=O)(=O)=O)c1)c1F

InChI

InChI=1S/C16H14FN3O4S/c1-8-3-4-10(6-11(8)17)20-25(23,24)14-7-13-12(5-9(14)2)18-15(21)16(22)19-13/h3-7,20H,1-2H3,(H,18,21)(H,19,22)

InChI Key

FTJWTVVIKQDPQZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913473

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.37

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.162

Distribution Coefficient, logD

1.468

Water Solubility, LogSw

-2.92

Polar Surface Area

90.723

Acid Dissociation Constant (pKa)

6.80

Base Dissociation Constant (pKb)

-2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

E734-0137 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Human Proteases Annotated Library (2868 compounds)

Purinergic Library (3321 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
  • Metabolic
  • Digestive system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-0137 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-0137?
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What is the minimum amount of E734-0137 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-0137
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-0137
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-0137 available by request