E734-0363 Screening compound: 1,4,7-trimethyl-2,3-dioxo-N-[4-(trifluoromethoxy)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

E734-0363 Screening compound: 1,4,7-trimethyl-2,3-dioxo-N-[4-(trifluoromethoxy)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide
E734-0363 Screening compound: 1,4,7-trimethyl-2,3-dioxo-N-[4-(trifluoromethoxy)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-0363
1,4,7-trimethyl-2,3-dioxo-N-[4-(trifluoromethoxy)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-0363

Molecular Formula

C18H16F3N3O5S (C18 H16 F3 N3 O5 S)

Compound Name

1,4,7-trimethyl-2,3-dioxo-N-[4-(trifluoromethoxy)phenyl]-1,2,3,4-tetrahydroquinoxaline-6-sulfonamide

IUPAC name

147-trimethyl-23-dioxo-N-[4-(trifluoromethoxy)phenyl]-1234-tetrahydroquinoxaline-6-sulfonamide

SMILES

Cc(cc(c(N(C)C1=O)c2)N(C)C1=O)c2S(Nc(cc1)ccc1OC(F)(F)F)(=O)=O

InChI

InChI=1S/C18H16F3N3O5S/c1-10-8-13-14(24(3)17(26)16(25)23(13)2)9-15(10)30(27,28)22-11-4-6-12(7-5-11)29-18(19,20)21/h4-9,22H,1-3H3

InChI Key

IJCBYLIDROJHEB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913550

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.4

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.832

Distribution Coefficient, logD

2.798

Water Solubility, LogSw

-3.55

Polar Surface Area

77.184

Acid Dissociation Constant (pKa)

8.48

Base Dissociation Constant (pKb)

-2.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

E734-0363 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer

References: we are preparing a list of scientific research reports with E734-0363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-0363?
Check Price and Availability of E734-0363, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E734-0363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-0363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-0363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-0363 available by request