E734-2404 Screening compound: N-(4-acetylphenyl)-4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide

E734-2404 Screening compound: N-(4-acetylphenyl)-4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide
E734-2404 Screening compound: N-(4-acetylphenyl)-4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2404
N-(4-acetylphenyl)-4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2404

Molecular Formula

C23H19N3O5S (C23 H19 N3 O5 S)

Compound Name

N-(4-acetylphenyl)-4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide

IUPAC name

N-(4-acetylphenyl)-4-(2-{57-dioxo-5H6H7H-pyrrolo[34-b]pyridin-6-yl}ethyl)benzene-1-sulfonamide

SMILES

CC(c(cc1)ccc1NS(c1ccc(CCN(C(c2c3nccc2)=O)C3=O)cc1)(=O)=O)=O

InChI

InChI=1S/C23H19N3O5S/c1-15(27)17-6-8-18(9-7-17)25-32(30,31)19-10-4-16(5-11-19)12-14-26-22(28)20-3-2-13-24-21(20)23(26)29/h2-11,13,25H,12,14H2,1H3

InChI Key

VXRGFYOFDRCGRJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913671

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.49

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.602

Distribution Coefficient, logD

0.836

Water Solubility, LogSw

-2.74

Polar Surface Area

93.855

Acid Dissociation Constant (pKa)

6.72

Base Dissociation Constant (pKb)

-5.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

E734-2404 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2404 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2404?
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What is the minimum amount of E734-2404 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2404
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2404
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2404 available by request