E734-2472 Screening compound: 6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

E734-2472 Screening compound: 6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione
E734-2472 Screening compound: 6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2472
6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2472

Molecular Formula

C19H19N3O4S (C19 H19 N3 O4 S)

Compound Name

6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

IUPAC name

6-{2-[4-(pyrrolidine-1-sulfonyl)phenyl]ethyl}-5H6H7H-pyrrolo[34-b]pyridine-57-dione

SMILES

O=C(c1c2nccc1)N(CCc(cc1)ccc1S(N1CCCC1)(=O)=O)C2=O

InChI

InChI=1S/C19H19N3O4S/c23-18-16-4-3-10-20-17(16)19(24)22(18)13-9-14-5-7-15(8-6-14)27(25,26)21-11-1-2-12-21/h3-8,10H,1-2,9,11-13H2

InChI Key

HLPZHFLAJGSUJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.051

Distribution Coefficient, logD

1.051

Water Solubility, LogSw

-2.35

Polar Surface Area

71.456

Acid Dissociation Constant (pKa)

26.20

Base Dissociation Constant (pKb)

-2.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.58

E734-2472 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2472 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2472?
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What is the minimum amount of E734-2472 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2472
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2472
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2472 available by request