E734-2484 Screening compound: 4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)-N-(3,4,5-trimethoxyphenyl)benzene-1-sulfonamide

E734-2484 Screening compound: 4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)-N-(3,4,5-trimethoxyphenyl)benzene-1-sulfonamide
E734-2484 Screening compound: 4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)-N-(3,4,5-trimethoxyphenyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2484
4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)-N-(3,4,5-trimethoxyphenyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2484

Molecular Formula

C24H23N3O7S (C24 H23 N3 O7 S)

Compound Name

4-(2-{5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}ethyl)-N-(3,4,5-trimethoxyphenyl)benzene-1-sulfonamide

IUPAC name

4-(2-{57-dioxo-5H6H7H-pyrrolo[34-b]pyridin-6-yl}ethyl)-N-(345-trimethoxyphenyl)benzene-1-sulfonamide

SMILES

COc1cc(NS(c2ccc(CCN(C(c3c4nccc3)=O)C4=O)cc2)(=O)=O)cc(OC)c1OC

InChI

InChI=1S/C24H23N3O7S/c1-32-19-13-16(14-20(33-2)22(19)34-3)26-35(30,31)17-8-6-15(7-9-17)10-12-27-23(28)18-5-4-11-25-21(18)24(27)29/h4-9,11,13-14,26H,10,12H2,1-3H3

InChI Key

YEOAFIFWWQMEJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913716

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.53

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.268

Distribution Coefficient, logD

0.341

Water Solubility, LogSw

-2.56

Polar Surface Area

103.006

Acid Dissociation Constant (pKa)

6.53

Base Dissociation Constant (pKb)

-5.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

E734-2484 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with E734-2484 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2484?
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What is the minimum amount of E734-2484 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2484
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2484
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2484 available by request