E734-2617 Screening compound: N-(5-chloropyridin-2-yl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

E734-2617 Screening compound: N-(5-chloropyridin-2-yl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide
E734-2617 Screening compound: N-(5-chloropyridin-2-yl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2617
N-(5-chloropyridin-2-yl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2617

Molecular Formula

C19H13ClN4O4S (C19 H13 ClN4 O4 S)

Compound Name

N-(5-chloropyridin-2-yl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

IUPAC name

N-(5-chloropyridin-2-yl)-4-({57-dioxo-5H6H7H-pyrrolo[34-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

SMILES

O=C(c1c2nccc1)N(Cc(cc1)ccc1S(Nc(cc1)ncc1Cl)(=O)=O)C2=O

InChI

InChI=1S/C19H13ClN4O4S/c20-13-5-8-16(22-10-13)23-29(27,28)14-6-3-12(4-7-14)11-24-18(25)15-2-1-9-21-17(15)19(24)26/h1-10H,11H2,(H,22,23)

InChI Key

DAKXPJFVCGRJHN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913772

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.86

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.939

Distribution Coefficient, logD

-0.358

Water Solubility, LogSw

-3.20

Polar Surface Area

89.754

Acid Dissociation Constant (pKa)

5.11

Base Dissociation Constant (pKb)

-1.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.30

E734-2617 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Neuropeptide S Library (2850 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Nervous system
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Proteases
  • Kinases
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2617 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2617?
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What is the minimum amount of E734-2617 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2617
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2617
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2617 available by request