E734-2687 Screening compound: 6-{[4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

E734-2687 Screening compound: 6-{[4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione
E734-2687 Screening compound: 6-{[4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2687
6-{[4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2687

Molecular Formula

C23H19N3O4S (C23 H19 N3 O4 S)

Compound Name

6-{[4-(1,2,3,4-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H,6H,7H-pyrrolo[3,4-b]pyridine-5,7-dione

IUPAC name

6-{[4-(1234-tetrahydroquinoline-1-sulfonyl)phenyl]methyl}-5H6H7H-pyrrolo[34-b]pyridine-57-dione

SMILES

O=C(c1c2nccc1)N(Cc(cc1)ccc1S(N(CCC1)c3c1cccc3)(=O)=O)C2=O

InChI

InChI=1S/C23H19N3O4S/c27-22-19-7-3-13-24-21(19)23(28)25(22)15-16-9-11-18(12-10-16)31(29,30)26-14-4-6-17-5-1-2-8-20(17)26/h1-3,5,7-13H,4,6,14-15H2

InChI Key

SGMYQMGPLXMGFH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913825

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.49

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.140

Distribution Coefficient, logD

2.140

Water Solubility, LogSw

-2.91

Polar Surface Area

70.553

Acid Dissociation Constant (pKa)

24.75

Base Dissociation Constant (pKb)

-6.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

E734-2687 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

GPCR Targeted Library (31838 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Nervous system
Targets:
  • Proteases
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2687 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2687?
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What is the minimum amount of E734-2687 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2687
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2687
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2687 available by request