E734-2761 Screening compound: N-(2-chloro-4-fluorophenyl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

E734-2761 Screening compound: N-(2-chloro-4-fluorophenyl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide
E734-2761 Screening compound: N-(2-chloro-4-fluorophenyl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2761
N-(2-chloro-4-fluorophenyl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2761

Molecular Formula

C20H13ClFN3O4S (C20 H13 ClFN3 O4 S)

Compound Name

N-(2-chloro-4-fluorophenyl)-4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

IUPAC name

N-(2-chloro-4-fluorophenyl)-4-({57-dioxo-5H6H7H-pyrrolo[34-b]pyridin-6-yl}methyl)benzene-1-sulfonamide

SMILES

O=C(c1c2nccc1)N(Cc(cc1)ccc1S(Nc(ccc(F)c1)c1Cl)(=O)=O)C2=O

InChI

InChI=1S/C20H13ClFN3O4S/c21-16-10-13(22)5-8-17(16)24-30(28,29)14-6-3-12(4-7-14)11-25-19(26)15-2-1-9-23-18(15)20(25)27/h1-10,24H,11H2

InChI Key

LMAFBCUZSJZPNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913877

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.86

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.622

Distribution Coefficient, logD

0.347

Water Solubility, LogSw

-3.58

Polar Surface Area

79.352

Acid Dissociation Constant (pKa)

5.13

Base Dissociation Constant (pKb)

-6.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

E734-2761 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Digestive system
  • Nervous system
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2761 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2761?
Check Price and Availability of E734-2761, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E734-2761 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2761
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2761
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2761 available by request