E734-2766 Screening compound: N-{4-[4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide

E734-2766 Screening compound: N-{4-[4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide
E734-2766 Screening compound: N-{4-[4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E734-2766
N-{4-[4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E734-2766

Molecular Formula

C22H18N4O5S (C22 H18 N4 O5 S)

Compound Name

N-{4-[4-({5,7-dioxo-5H,6H,7H-pyrrolo[3,4-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide

IUPAC name

N-{4-[4-({57-dioxo-5H6H7H-pyrrolo[34-b]pyridin-6-yl}methyl)benzenesulfonamido]phenyl}acetamide

SMILES

CC(Nc(cc1)ccc1NS(c1ccc(CN(C(c2c3nccc2)=O)C3=O)cc1)(=O)=O)=O

InChI

InChI=1S/C22H18N4O5S/c1-14(27)24-16-6-8-17(9-7-16)25-32(30,31)18-10-4-15(5-11-18)13-26-21(28)19-3-2-12-23-20(19)22(26)29/h2-12,25H,13H2,1H3,(H,24,27)

InChI Key

OIJUXDROVHFIQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14913881

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.47

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.220

Distribution Coefficient, logD

1.198

Water Solubility, LogSw

-2.52

Polar Surface Area

103.312

Acid Dissociation Constant (pKa)

8.70

Base Dissociation Constant (pKb)

2.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

E734-2766 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antimitotic Tubulin Library (17355 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Dark Chemical Matter Library (18430 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Neuropeptide S Library (2850 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Digestive system
  • Nervous system
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E734-2766 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E734-2766?
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What is the minimum amount of E734-2766 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E734-2766
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E734-2766
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E734-2766 available by request