E746-0061 Screening compound: 1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine

E746-0061 Screening compound: 1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine
E746-0061 Screening compound: 1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E746-0061
1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E746-0061

Molecular Formula

C26H26N4O2S (C26 H26 N4 O2 S)

Compound Name

1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine

IUPAC name

1-(diphenylmethyl)-4-[4-(1H-pyrazol-1-yl)benzenesulfonyl]piperazine

SMILES

O=S(c(cc1)ccc1-n1nccc1)(N(CC1)CCN1C(c1ccccc1)c1ccccc1)=O

InChI

InChI=1S/C26H26N4O2S/c31-33(32,25-14-12-24(13-15-25)30-17-7-16-27-30)29-20-18-28(19-21-29)26(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-17,26H,18-21H2

InChI Key

LJTZEINDQOHKAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14914795

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.600

Distribution Coefficient, logD

4.600

Water Solubility, LogSw

-4.53

Polar Surface Area

48.886

Acid Dissociation Constant (pKa)

25.05

Base Dissociation Constant (pKb)

4.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

E746-0061 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

DGK Inhibitors Library (10558 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E746-0061 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E746-0061?
Check Price and Availability of E746-0061, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E746-0061 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E746-0061
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E746-0061
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E746-0061 available by request