E746-0723 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one

E746-0723 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one
E746-0723 Screening compound: 3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E746-0723
3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E746-0723

Molecular Formula

C21H31N3O4S (C21 H31 N3 O4 S)

Compound Name

3-[(1-acetyl-2,3-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one

IUPAC name

3-[(1-acetyl-23-dihydro-1H-indol-5-yl)sulfonyl]-1-(4-propylpiperazin-1-yl)butan-1-one

SMILES

CCCN(CC1)CCN1C(CC(C)S(c(cc1)cc(CC2)c1N2C(C)=O)(=O)=O)=O

InChI

InChI=1S/C21H31N3O4S/c1-4-8-22-10-12-23(13-11-22)21(26)14-16(2)29(27,28)19-5-6-20-18(15-19)7-9-24(20)17(3)25/h5-6,15-16H,4,7-14H2,1-3H3/t16-/m0/s1

InChI Key

IMWMTTSCGKTBOU-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14914937

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.994

Distribution Coefficient, logD

0.664

Water Solubility, LogSw

-2.35

Polar Surface Area

66.340

Acid Dissociation Constant (pKa)

18.79

Base Dissociation Constant (pKb)

7.46

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

61.90

E746-0723 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E746-0723 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E746-0723?
Check Price and Availability of E746-0723, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E746-0723 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E746-0723
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E746-0723
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E746-0723 available by request