E746-1805 Screening compound: methyl 4-[(2-chloro-4,6-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate

E746-1805 Screening compound: methyl 4-[(2-chloro-4,6-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate
E746-1805 Screening compound: methyl 4-[(2-chloro-4,6-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E746-1805
methyl 4-[(2-chloro-4,6-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E746-1805

Molecular Formula

C14H15ClN2O6S (C14 H15 ClN2 O6 S)

Compound Name

methyl 4-[(2-chloro-4,6-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate

IUPAC name

methyl 4-[(2-chloro-46-dimethoxyphenyl)sulfamoyl]-1H-pyrrole-2-carboxylate

SMILES

COC(c1cc(S(Nc(c(OC)cc(OC)c2)c2Cl)(=O)=O)c[nH]1)=O

InChI

InChI=1S/C14H15ClN2O6S/c1-21-8-4-10(15)13(12(5-8)22-2)17-24(19,20)9-6-11(16-7-9)14(18)23-3/h4-7,16-17H,1-3H3

InChI Key

WXRMIMQCNQQYGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14914974

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.8

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.912

Distribution Coefficient, logD

0.789

Water Solubility, LogSw

-2.77

Polar Surface Area

85.996

Acid Dissociation Constant (pKa)

6.31

Base Dissociation Constant (pKb)

-4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

E746-1805 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E746-1805 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E746-1805?
Check Price and Availability of E746-1805, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E746-1805 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E746-1805
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E746-1805
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E746-1805 available by request