E755-0223 Screening compound: N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide

E755-0223 Screening compound: N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide
E755-0223 Screening compound: N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E755-0223
N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E755-0223

Molecular Formula

C23H20FN5O7S (C23 H20 FN5 O7 S)

Compound Name

N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide

IUPAC name

N-(2-fluorophenyl)-2-(2-{[(6-hydroxy-24-dioxo-1234-tetrahydropyrimidin-5-yl)(4-hydroxy-3-methoxyphenyl)methyl]amino}-4-oxo-45-dihydro-13-thiazol-5-yl)acetamide

SMILES

COc(cc(C(C(C(NC(N1)=O)=O)=C1O)NC(SC1CC(Nc(cccc2)c2F)=O)=NC1=O)cc1)c1O

InChI

InChI=1S/C23H20FN5O7S/c1-36-14-8-10(6-7-13(14)30)18(17-20(33)27-22(35)28-21(17)34)26-23-29-19(32)15(37-23)9-16(31)25-12-5-3-2-4-11(12)24/h2-8,15,18,30H,9H2,1H3,(H,25,31)(H,26,29,32)(H3,27,28,33,34,35)

InChI Key

IBKURDYOMOQVGR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14915976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

529.51

Hydrogen Bond Acceptors Count

13.00

Hydrogen Bond Donors Count

6.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

0.041

Distribution Coefficient, logD

-4.257

Water Solubility, LogSw

-2.28

Polar Surface Area

143.711

Acid Dissociation Constant (pKa)

3.10

Base Dissociation Constant (pKb)

-0.49

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

17.40

References: we are preparing a list of scientific research reports with E755-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E755-0223?
Check Price and Availability of E755-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E755-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E755-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E755-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E755-0223 available by request