E760-0067 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{3H-imidazo[4,5-b]pyridin-3-yl}benzamide

E760-0067 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{3H-imidazo[4,5-b]pyridin-3-yl}benzamide
E760-0067 Screening compound: N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{3H-imidazo[4,5-b]pyridin-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-0067
N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{3H-imidazo[4,5-b]pyridin-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-0067

Molecular Formula

C21H16N4O3 (C21 H16 N4 O3)

Compound Name

N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{3H-imidazo[4,5-b]pyridin-3-yl}benzamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-{3H-imidazo[45-b]pyridin-3-yl}benzamide

SMILES

O=C(c(cc1)ccc1-n1c2ncccc2nc1)NCc(cc1)cc2c1OCO2

InChI

InChI=1S/C21H16N4O3/c26-21(23-11-14-3-8-18-19(10-14)28-13-27-18)15-4-6-16(7-5-15)25-12-24-17-2-1-9-22-20(17)25/h1-10,12H,11,13H2,(H,23,26)

InChI Key

HSFOPQNGPYLFLO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916479

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.463

Distribution Coefficient, logD

2.463

Water Solubility, LogSw

-2.98

Polar Surface Area

62.318

Acid Dissociation Constant (pKa)

13.01

Base Dissociation Constant (pKb)

4.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

E760-0067 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E760-0067 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-0067?
Check Price and Availability of E760-0067, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-0067 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-0067
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-0067
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-0067 available by request