E760-1245 Screening compound: 1-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperidine

E760-1245 Screening compound: 1-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperidine
E760-1245 Screening compound: 1-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-1245
1-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-1245

Molecular Formula

C24H22N4O (C24 H22 N4 O)

Compound Name

1-(4-{2-phenyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperidine

IUPAC name

1-(4-{2-phenyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)piperidine

SMILES

O=C(c(cc1)ccc1-n1c(-c2ccccc2)nc2cccnc12)N1CCCCC1

InChI

InChI=1S/C24H22N4O/c29-24(27-16-5-2-6-17-27)19-11-13-20(14-12-19)28-22(18-8-3-1-4-9-18)26-21-10-7-15-25-23(21)28/h1,3-4,7-15H,2,5-6,16-17H2

InChI Key

CTYQLKYFOHBAGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916605

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.041

Distribution Coefficient, logD

4.041

Water Solubility, LogSw

-4.21

Polar Surface Area

37.194

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

4.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

E760-1245 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E760-1245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-1245?
Check Price and Availability of E760-1245, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-1245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-1245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-1245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-1245 available by request