E760-3226 Screening compound: 2-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide

E760-3226 Screening compound: 2-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide
E760-3226 Screening compound: 2-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-3226
2-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-3226

Molecular Formula

C21H24N4O2 (C21 H24 N4 O2)

Compound Name

2-(4-{2-ethyl-3H-imidazo[4,5-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide

IUPAC name

2-(4-{2-ethyl-3H-imidazo[45-b]pyridin-3-yl}phenyl)-N-[(oxolan-2-yl)methyl]acetamide

SMILES

CCc1nc2cccnc2n1-c1ccc(CC(NCC2OCCC2)=O)cc1

InChI

InChI=1S/C21H24N4O2/c1-2-19-24-18-6-3-11-22-21(18)25(19)16-9-7-15(8-10-16)13-20(26)23-14-17-5-4-12-27-17/h3,6-11,17H,2,4-5,12-14H2,1H3,(H,23,26)/t17-/m1/s1

InChI Key

OKWOXDDUCMTZAL-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD14916676

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.778

Distribution Coefficient, logD

1.777

Water Solubility, LogSw

-2.03

Polar Surface Area

54.647

Acid Dissociation Constant (pKa)

13.77

Base Dissociation Constant (pKb)

4.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

E760-3226 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Purinergic Library (3321 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Cardiovascular
  • Metabolic
Targets:
  • Kinases
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E760-3226 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-3226?
Check Price and Availability of E760-3226, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-3226 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-3226
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-3226
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-3226 available by request