E760-5354 Screening compound: 4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)morpholine

E760-5354 Screening compound: 4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)morpholine
E760-5354 Screening compound: 4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-5354
4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-5354

Molecular Formula

C18H18N4O2 (C18 H18 N4 O2)

Compound Name

4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)morpholine

IUPAC name

4-(3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)morpholine

SMILES

Cc1nc2cccnc2n1-c1cccc(C(N2CCOCC2)=O)c1

InChI

InChI=1S/C18H18N4O2/c1-13-20-16-6-3-7-19-17(16)22(13)15-5-2-4-14(12-15)18(23)21-8-10-24-11-9-21/h2-7,12H,8-11H2,1H3

InChI Key

WICHEDZPMAEBNC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916807

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

322.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.063

Distribution Coefficient, logD

1.062

Water Solubility, LogSw

-1.76

Polar Surface Area

46.151

Acid Dissociation Constant (pKa)

28.82

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

E760-5354 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Cardiovascular Library (22201 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E760-5354 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-5354?
Check Price and Availability of E760-5354, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-5354 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-5354
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-5354
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-5354 available by request