E760-5360 Screening compound: [3-(2-METHYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)PHENYL](4-PROPYLPIPERAZINO)METHANONE

E760-5360 Screening compound: [3-(2-METHYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)PHENYL](4-PROPYLPIPERAZINO)METHANONE
E760-5360 Screening compound: [3-(2-METHYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)PHENYL](4-PROPYLPIPERAZINO)METHANONE alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-5360
[3-(2-METHYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)PHENYL](4-PROPYLPIPERAZINO)METHANONE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-5360

Molecular Formula

C21H25N5O (C21 H25 N5 O)

Compound Name

[3-(2-METHYL-3H-IMIDAZO[4,5-B]PYRIDIN-3-YL)PHENYL](4-PROPYLPIPERAZINO)METHANONE

IUPAC name

1-(3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)-4-propylpiperazine

SMILES

CCCN(CC1)CCN1C(c1cc(-n2c3ncccc3nc2C)ccc1)=O

InChI

InChI=1S/C21H25N5O/c1-3-10-24-11-13-25(14-12-24)21(27)17-6-4-7-18(15-17)26-16(2)23-19-8-5-9-22-20(19)26/h4-9,15H,3,10-14H2,1-2H3

InChI Key

CHPMPPRVMCWNJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916808

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.852

Distribution Coefficient, logD

1.669

Water Solubility, LogSw

-1.95

Polar Surface Area

42.033

Acid Dissociation Constant (pKa)

27.99

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

E760-5360 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Ion Channels
  • Kinases

References: we are preparing a list of scientific research reports with E760-5360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-5360?
Check Price and Availability of E760-5360, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-5360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-5360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-5360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-5360 available by request