E760-5381 Screening compound: 1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

E760-5381 Screening compound: 1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine
E760-5381 Screening compound: 1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-5381
1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-5381

Molecular Formula

C24H22FN5O (C24 H22 FN5 O)

Compound Name

1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzoyl)piperazine

IUPAC name

1-(4-fluorophenyl)-4-(3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzoyl)piperazine

SMILES

Cc1nc2cccnc2n1-c1cccc(C(N(CC2)CCN2c(cc2)ccc2F)=O)c1

InChI

InChI=1S/C24H22FN5O/c1-17-27-22-6-3-11-26-23(22)30(17)21-5-2-4-18(16-21)24(31)29-14-12-28(13-15-29)20-9-7-19(25)8-10-20/h2-11,16H,12-15H2,1H3

InChI Key

BXAXAVIUSLDKNE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916818

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.47

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.007

Distribution Coefficient, logD

3.007

Water Solubility, LogSw

-3.04

Polar Surface Area

41.503

Acid Dissociation Constant (pKa)

28.00

Base Dissociation Constant (pKb)

4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

E760-5381 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E760-5381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-5381?
Check Price and Availability of E760-5381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-5381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-5381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-5381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-5381 available by request