E760-5481 Screening compound: N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

E760-5481 Screening compound: N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide
E760-5481 Screening compound: N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-5481
N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-5481

Molecular Formula

C28H32N6O2 (C28 H32 N6 O2)

Compound Name

N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

IUPAC name

N-{3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl}-3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzamide

SMILES

Cc1nc2cccnc2n1-c1cccc(C(NCCCN(CC2)CCN2c(cc2)ccc2OC)=O)c1

InChI

InChI=1S/C28H32N6O2/c1-21-31-26-8-4-13-29-27(26)34(21)24-7-3-6-22(20-24)28(35)30-14-5-15-32-16-18-33(19-17-32)23-9-11-25(36-2)12-10-23/h3-4,6-13,20H,5,14-19H2,1-2H3,(H,30,35)

InChI Key

ANSIZZVSELRRFM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14916835

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.920

Distribution Coefficient, logD

2.376

Water Solubility, LogSw

-3.32

Polar Surface Area

60.636

Acid Dissociation Constant (pKa)

14.34

Base Dissociation Constant (pKb)

7.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

E760-5481 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Proline Kinase Library (2105 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E760-5481 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-5481?
Check Price and Availability of E760-5481, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-5481 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-5481
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-5481
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-5481 available by request