E760-7737 Screening compound: N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

E760-7737 Screening compound: N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide
E760-7737 Screening compound: N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E760-7737
N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E760-7737

Molecular Formula

C26H26ClN5O (C26 H26 ClN5 O)

Compound Name

N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}benzamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-4-chloro-3-{2-methyl-3H-imidazo[45-b]pyridin-3-yl}benzamide

SMILES

Cc1nc2cccnc2n1-c(cc(cc1)C(NC2CCN(Cc3ccccc3)CC2)=O)c1Cl

InChI

InChI=1S/C26H26ClN5O/c1-18-29-23-8-5-13-28-25(23)32(18)24-16-20(9-10-22(24)27)26(33)30-21-11-14-31(15-12-21)17-19-6-3-2-4-7-19/h2-10,13,16,21H,11-12,14-15,17H2,1H3,(H,30,33)

InChI Key

JPBQQSMXRDVENV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27601280

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.578

Distribution Coefficient, logD

2.133

Water Solubility, LogSw

-3.99

Polar Surface Area

48.972

Acid Dissociation Constant (pKa)

14.02

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

E760-7737 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E760-7737 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E760-7737?
Check Price and Availability of E760-7737, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E760-7737 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E760-7737
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E760-7737
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E760-7737 available by request