E769-0667 Screening compound: 3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

E769-0667 Screening compound: 3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea
E769-0667 Screening compound: 3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E769-0667
3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E769-0667

Molecular Formula

C25H27N3O3S (C25 H27 N3 O3 S)

Compound Name

3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

IUPAC name

3-(2-methoxyethyl)-1-(2-methoxyphenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

SMILES

Cn1c(-c2cccs2)c(CN(CCOC)C(Nc(cccc2)c2OC)=O)c2c1cccc2

InChI

InChI=1S/C25H27N3O3S/c1-27-21-11-6-4-9-18(21)19(24(27)23-13-8-16-32-23)17-28(14-15-30-2)25(29)26-20-10-5-7-12-22(20)31-3/h4-13,16H,14-15,17H2,1-3H3,(H,26,29)

InChI Key

RGIJZJGTWVHRGJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27601431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.57

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.970

Distribution Coefficient, logD

4.970

Water Solubility, LogSw

-4.81

Polar Surface Area

42.582

Acid Dissociation Constant (pKa)

12.82

Base Dissociation Constant (pKb)

2.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

E769-0667 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E769-0667 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E769-0667?
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What is the minimum amount of E769-0667 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E769-0667
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E769-0667
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E769-0667 available by request