E769-0728 Screening compound: 1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

E769-0728 Screening compound: 1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea
E769-0728 Screening compound: 1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E769-0728
1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E769-0728

Molecular Formula

C23H25N3O3S (C23 H25 N3 O3 S)

Compound Name

1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

IUPAC name

1-[(furan-2-yl)methyl]-3-(2-methoxyethyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

SMILES

Cn1c(-c2cccs2)c(CN(CCOC)C(NCc2ccco2)=O)c2c1cccc2

InChI

InChI=1S/C23H25N3O3S/c1-25-20-9-4-3-8-18(20)19(22(25)21-10-6-14-30-21)16-26(11-13-28-2)23(27)24-15-17-7-5-12-29-17/h3-10,12,14H,11,13,15-16H2,1-2H3,(H,24,27)

InChI Key

QKENNQFZWRCZTI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27601468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.199

Distribution Coefficient, logD

4.199

Water Solubility, LogSw

-4.11

Polar Surface Area

44.720

Acid Dissociation Constant (pKa)

14.57

Base Dissociation Constant (pKb)

-0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

E769-0728 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Infections
  • Immune system
  • animal
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E769-0728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E769-0728?
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What is the minimum amount of E769-0728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E769-0728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E769-0728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E769-0728 available by request