E769-1205 Screening compound: 1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

E769-1205 Screening compound: 1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea
E769-1205 Screening compound: 1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound E769-1205
1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E769-1205

Molecular Formula

C21H18ClN3OS (C21 H18 ClN3 OS)

Compound Name

1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

IUPAC name

1-(3-chlorophenyl)-3-{[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl}urea

SMILES

Cn1c(-c2cccs2)c(CNC(Nc2cccc(Cl)c2)=O)c2c1cccc2

InChI

InChI=1S/C21H18ClN3OS/c1-25-18-9-3-2-8-16(18)17(20(25)19-10-5-11-27-19)13-23-21(26)24-15-7-4-6-14(22)12-15/h2-12H,13H2,1H3,(H2,23,24,26)

InChI Key

PXTPCPAERWFNGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27601498

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.91

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.610

Distribution Coefficient, logD

5.610

Water Solubility, LogSw

-5.94

Polar Surface Area

35.922

Acid Dissociation Constant (pKa)

11.69

Base Dissociation Constant (pKb)

-1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

E769-1205 in Drug Discovery

Included in Screening Libraries

3CLpro Library (4801 compounds)

Anti-Aging Library (44940 compounds)

CORONAVIRUS Library (20774 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E769-1205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E769-1205?
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What is the minimum amount of E769-1205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E769-1205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E769-1205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E769-1205 available by request