E769-1653 Screening compound: methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate

E769-1653 Screening compound: methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate
E769-1653 Screening compound: methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E769-1653
methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E769-1653

Molecular Formula

C24H25N3O4S2 (C24 H25 N3 O4 S2)

Compound Name

methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate

IUPAC name

methyl 3-{[(2-methoxyethyl)({[1-methyl-2-(thiophen-2-yl)-1H-indol-3-yl]methyl})carbamoyl]amino}thiophene-2-carboxylate

SMILES

Cn1c(-c2cccs2)c(CN(CCOC)C(Nc2c(C(OC)=O)scc2)=O)c2c1cccc2

InChI

InChI=1S/C24H25N3O4S2/c1-26-19-8-5-4-7-16(19)17(21(26)20-9-6-13-32-20)15-27(11-12-30-2)24(29)25-18-10-14-33-22(18)23(28)31-3/h4-10,13-14H,11-12,15H2,1-3H3,(H,25,29)

InChI Key

HXMOZTURPAZSIX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27601706

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.61

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.635

Distribution Coefficient, logD

4.634

Water Solubility, LogSw

-4.26

Polar Surface Area

57.144

Acid Dissociation Constant (pKa)

10.03

Base Dissociation Constant (pKb)

-1.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

E769-1653 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E769-1653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E769-1653?
Check Price and Availability of E769-1653, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E769-1653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E769-1653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E769-1653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E769-1653 available by request