E771-0382 Screening compound: 4-(1H-indol-3-yl)-N-(4-methylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxamide

E771-0382 Screening compound: 4-(1H-indol-3-yl)-N-(4-methylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxamide
E771-0382 Screening compound: 4-(1H-indol-3-yl)-N-(4-methylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E771-0382
4-(1H-indol-3-yl)-N-(4-methylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E771-0382

Molecular Formula

C21H21N3O (C21 H21 N3 O)

Compound Name

4-(1H-indol-3-yl)-N-(4-methylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxamide

IUPAC name

4-(1H-indol-3-yl)-N-(4-methylphenyl)-1236-tetrahydropyridine-1-carboxamide

SMILES

Cc(cc1)ccc1NC(N(CC1)CC=C1c1c[nH]c2c1cccc2)=O

InChI

InChI=1S/C21H21N3O/c1-15-6-8-17(9-7-15)23-21(25)24-12-10-16(11-13-24)19-14-22-20-5-3-2-4-18(19)20/h2-10,14,22H,11-13H2,1H3,(H,23,25)

InChI Key

HECLHVPOESQOEF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD10372945

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

331.42

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.727

Distribution Coefficient, logD

4.727

Water Solubility, LogSw

-4.56

Polar Surface Area

35.307

Acid Dissociation Constant (pKa)

13.73

Base Dissociation Constant (pKb)

1.34

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

E771-0382 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

GABA Library (7115 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Eye
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E771-0382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E771-0382?
Check Price and Availability of E771-0382, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E771-0382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E771-0382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E771-0382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E771-0382 available by request