E772-0257 Screening compound: 1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one

E772-0257 Screening compound: 1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one
E772-0257 Screening compound: 1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E772-0257
1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E772-0257

Molecular Formula

C26H25ClN4O2S (C26 H25 ClN4 O2 S)

Compound Name

1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H,2H,3H-pyrido[2,3-b][1,4]thiazin-2-one

IUPAC name

1-({4-[4-(5-chloro-2-methylphenyl)piperazine-1-carbonyl]phenyl}methyl)-1H2H3H-pyrido[23-b][14]thiazin-2-one

SMILES

Cc(ccc(Cl)c1)c1N(CC1)CCN1C(c1ccc(CN2c(cccn3)c3SCC2=O)cc1)=O

InChI

InChI=1S/C26H25ClN4O2S/c1-18-4-9-21(27)15-23(18)29-11-13-30(14-12-29)26(33)20-7-5-19(6-8-20)16-31-22-3-2-10-28-25(22)34-17-24(31)32/h2-10,15H,11-14,16-17H2,1H3

InChI Key

LFPCCPYSXKXVNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14917427

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

493.03

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.331

Distribution Coefficient, logD

4.331

Water Solubility, LogSw

-4.50

Polar Surface Area

46.279

Acid Dissociation Constant (pKa)

17.64

Base Dissociation Constant (pKb)

3.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

References: we are preparing a list of scientific research reports with E772-0257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E772-0257?
Check Price and Availability of E772-0257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E772-0257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E772-0257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E772-0257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E772-0257 available by request