E783-0095 Screening compound: 8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H,4H-chromeno[3,4-d]imidazol-4-one

E783-0095 Screening compound: 8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H,4H-chromeno[3,4-d]imidazol-4-one
E783-0095 Screening compound: 8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H,4H-chromeno[3,4-d]imidazol-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E783-0095
8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H,4H-chromeno[3,4-d]imidazol-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E783-0095

Molecular Formula

C21H19ClN4O4S (C21 H19 ClN4 O4 S)

Compound Name

8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H,4H-chromeno[3,4-d]imidazol-4-one

IUPAC name

8-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-1-methyl-1H4H-chromeno[34-d]imidazol-4-one

SMILES

Cn1c(-c(cc(cc2)S(N(CC3)CCN3c3cccc(Cl)c3)(=O)=O)c2OC2=O)c2nc1

InChI

InChI=1S/C21H19ClN4O4S/c1-24-13-23-19-20(24)17-12-16(5-6-18(17)30-21(19)27)31(28,29)26-9-7-25(8-10-26)15-4-2-3-14(22)11-15/h2-6,11-13H,7-10H2,1H3

InChI Key

MBFRELXMKRMVOE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14918374

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.93

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.863

Distribution Coefficient, logD

2.863

Water Solubility, LogSw

-3.55

Polar Surface Area

67.885

Acid Dissociation Constant (pKa)

26.20

Base Dissociation Constant (pKb)

1.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

E783-0095 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antimitotic Tubulin Library (17355 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with E783-0095 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E783-0095?
Check Price and Availability of E783-0095, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E783-0095 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E783-0095
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E783-0095
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E783-0095 available by request