E783-0159 Screening compound: N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H,4H-chromeno[3,4-d]imidazole-8-sulfonamide

E783-0159 Screening compound: N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H,4H-chromeno[3,4-d]imidazole-8-sulfonamide
E783-0159 Screening compound: N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H,4H-chromeno[3,4-d]imidazole-8-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E783-0159
N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H,4H-chromeno[3,4-d]imidazole-8-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E783-0159

Molecular Formula

C24H27N5O5S (C24 H27 N5 O5 S)

Compound Name

N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H,4H-chromeno[3,4-d]imidazole-8-sulfonamide

IUPAC name

N-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}-1-methyl-4-oxo-1H4H-chromeno[34-d]imidazole-8-sulfonamide

SMILES

Cn1c(-c(cc(cc2)S(NCCN(CC3)CCN3c(cc3)ccc3OC)(=O)=O)c2OC2=O)c2nc1

InChI

InChI=1S/C24H27N5O5S/c1-27-16-25-22-23(27)20-15-19(7-8-21(20)34-24(22)30)35(31,32)26-9-10-28-11-13-29(14-12-28)17-3-5-18(33-2)6-4-17/h3-8,15-16,26H,9-14H2,1-2H3

InChI Key

PNDFYWQOSYZGCW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09696814

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.167

Distribution Coefficient, logD

2.154

Water Solubility, LogSw

-3.09

Polar Surface Area

89.300

Acid Dissociation Constant (pKa)

11.50

Base Dissociation Constant (pKb)

5.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

E783-0159 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E783-0159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E783-0159?
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What is the minimum amount of E783-0159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E783-0159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E783-0159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E783-0159 available by request