E822-0466 Screening compound: 4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine

E822-0466 Screening compound: 4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine
E822-0466 Screening compound: 4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E822-0466
4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E822-0466

Molecular Formula

C19H23N3O (C19 H23 N3 O)

Compound Name

4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine

IUPAC name

4-benzyl-1-(3-cyclopropyl-1H-pyrazole-5-carbonyl)piperidine

SMILES

O=C(c1cc(C2CC2)n[nH]1)N1CCC(Cc2ccccc2)CC1

InChI

InChI=1S/C19H23N3O/c23-19(18-13-17(20-21-18)16-6-7-16)22-10-8-15(9-11-22)12-14-4-2-1-3-5-14/h1-5,13,15-16H,6-12H2,(H,20,21)

InChI Key

VCJXFCVBTDZYCF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14920144

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

309.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.073

Distribution Coefficient, logD

4.073

Water Solubility, LogSw

-4.26

Polar Surface Area

39.628

Acid Dissociation Constant (pKa)

9.62

Base Dissociation Constant (pKb)

4.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.40

E822-0466 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Nucleic Acid Ligands (8311 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
  • Epigenetic
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with E822-0466 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E822-0466?
Check Price and Availability of E822-0466, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E822-0466 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E822-0466
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E822-0466
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E822-0466 available by request