E843-1363 Screening compound: 7-[3-(3-phenyl-1,2,4-oxadiazol-5-yl)propyl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinazoline-6,8-dione

E843-1363 Screening compound: 7-[3-(3-phenyl-1,2,4-oxadiazol-5-yl)propyl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinazoline-6,8-dione
E843-1363 Screening compound: 7-[3-(3-phenyl-1,2,4-oxadiazol-5-yl)propyl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinazoline-6,8-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound E843-1363
7-[3-(3-phenyl-1,2,4-oxadiazol-5-yl)propyl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinazoline-6,8-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E843-1363

Molecular Formula

C20H16N4O5 (C20 H16 N4 O5)

Compound Name

7-[3-(3-phenyl-1,2,4-oxadiazol-5-yl)propyl]-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]quinazoline-6,8-dione

IUPAC name

7-[3-(3-phenyl-124-oxadiazol-5-yl)propyl]-2H5H6H7H8H-[13]dioxolo[45-g]quinazoline-68-dione

SMILES

O=C(c(cc1OCOc1c1)c1N1)N(CCCc2nc(-c3ccccc3)no2)C1=O

InChI

InChI=1S/C20H16N4O5/c25-19-13-9-15-16(28-11-27-15)10-14(13)21-20(26)24(19)8-4-7-17-22-18(23-29-17)12-5-2-1-3-6-12/h1-3,5-6,9-10H,4,7-8,11H2,(H,21,26)

InChI Key

BXLHTXGYLCHHFK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14920848

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.37

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.475

Distribution Coefficient, logD

3.459

Water Solubility, LogSw

-3.76

Polar Surface Area

88.917

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

-4.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

E843-1363 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E843-1363 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E843-1363?
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What is the minimum amount of E843-1363 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E843-1363
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E843-1363
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E843-1363 available by request