E844-1365 Screening compound: 8-fluoro-2,5-bis[(2-fluorophenyl)methyl]-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one

E844-1365 Screening compound: 8-fluoro-2,5-bis[(2-fluorophenyl)methyl]-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one
E844-1365 Screening compound: 8-fluoro-2,5-bis[(2-fluorophenyl)methyl]-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E844-1365
8-fluoro-2,5-bis[(2-fluorophenyl)methyl]-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E844-1365

Molecular Formula

C24H16F3N3O (C24 H16 F3 N3 O)

Compound Name

8-fluoro-2,5-bis[(2-fluorophenyl)methyl]-2H,3H,5H-pyrazolo[4,3-c]quinolin-3-one

IUPAC name

8-fluoro-25-bis[(2-fluorophenyl)methyl]-2H3H5H-pyrazolo[43-c]quinolin-3-one

SMILES

O=C1N(Cc(cccc2)c2F)N=C2c(cc(cc3)F)c3N(Cc(cccc3)c3F)C=C12

InChI

InChI=1S/C24H16F3N3O/c25-17-9-10-22-18(11-17)23-19(14-29(22)12-15-5-1-3-7-20(15)26)24(31)30(28-23)13-16-6-2-4-8-21(16)27/h1-11,14H,12-13H2

InChI Key

DDTWWRDKSBSFSA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14920870

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.717

Distribution Coefficient, logD

4.717

Water Solubility, LogSw

-4.85

Polar Surface Area

29.504

Acid Dissociation Constant (pKa)

22.59

Base Dissociation Constant (pKb)

3.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

E844-1365 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E844-1365 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E844-1365?
Check Price and Availability of E844-1365, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E844-1365 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E844-1365
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E844-1365
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E844-1365 available by request