E848-0335 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

E848-0335 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide
E848-0335 Screening compound: N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E848-0335
N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E848-0335

Molecular Formula

C23H26ClN3O3S (C23 H26 ClN3 O3 S)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

SMILES

O=C(Cn(cc1)c(cc2)c1cc2S(N1CCCCC1)(=O)=O)NCCc(cc1)ccc1Cl

InChI

InChI=1S/C23H26ClN3O3S/c24-20-6-4-18(5-7-20)10-12-25-23(28)17-26-15-11-19-16-21(8-9-22(19)26)31(29,30)27-13-2-1-3-14-27/h4-9,11,15-16H,1-3,10,12-14,17H2,(H,25,28)

InChI Key

LJXDTDXFAIQAQP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921061

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.581

Distribution Coefficient, logD

3.581

Water Solubility, LogSw

-3.90

Polar Surface Area

58.101

Acid Dissociation Constant (pKa)

14.14

Base Dissociation Constant (pKb)

1.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

E848-0335 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

GPCR Targeted Library (31838 compounds)

Human Proteases Annotated Library (2868 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E848-0335 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E848-0335?
Check Price and Availability of E848-0335, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E848-0335 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E848-0335
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E848-0335
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E848-0335 available by request