E848-0455 Screening compound: N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

E848-0455 Screening compound: N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide
E848-0455 Screening compound: N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E848-0455
N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E848-0455

Molecular Formula

C23H34N4O3S (C23 H34 N4 O3 S)

Compound Name

N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

IUPAC name

N-[3-(piperidin-1-yl)propyl]-2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]acetamide

SMILES

O=C(Cn(cc1)c(cc2)c1cc2S(N1CCCCC1)(=O)=O)NCCCN1CCCCC1

InChI

InChI=1S/C23H34N4O3S/c28-23(24-11-7-14-25-12-3-1-4-13-25)19-26-17-10-20-18-21(8-9-22(20)26)31(29,30)27-15-5-2-6-16-27/h8-10,17-18H,1-7,11-16,19H2,(H,24,28)

InChI Key

NMXHLOJQGMYAJT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921102

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.61

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.355

Distribution Coefficient, logD

-0.299

Water Solubility, LogSw

-3.04

Polar Surface Area

62.084

Acid Dissociation Constant (pKa)

15.28

Base Dissociation Constant (pKb)

10.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.90

E848-0455 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

MCL1 Targeted Library (12200 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • GPCR
  • Phosphatases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E848-0455 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E848-0455?
Check Price and Availability of E848-0455, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E848-0455 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E848-0455
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E848-0455
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E848-0455 available by request