E848-0549 Screening compound: 2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

E848-0549 Screening compound: 2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one
E848-0549 Screening compound: 2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E848-0549
2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E848-0549

Molecular Formula

C24H29N5O3S (C24 H29 N5 O3 S)

Compound Name

2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

IUPAC name

2-[5-(piperidine-1-sulfonyl)-1H-indol-1-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]ethan-1-one

SMILES

O=C(Cn(cc1)c(cc2)c1cc2S(N1CCCCC1)(=O)=O)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H29N5O3S/c30-24(27-16-14-26(15-17-27)23-6-2-3-10-25-23)19-28-13-9-20-18-21(7-8-22(20)28)33(31,32)29-11-4-1-5-12-29/h2-3,6-10,13,18H,1,4-5,11-12,14-17,19H2

InChI Key

CVOZVUAKYAOPPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921131

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.874

Distribution Coefficient, logD

2.865

Water Solubility, LogSw

-3.19

Polar Surface Area

61.953

Acid Dissociation Constant (pKa)

23.10

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

E848-0549 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system

References: we are preparing a list of scientific research reports with E848-0549 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E848-0549?
Check Price and Availability of E848-0549, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E848-0549 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E848-0549
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E848-0549
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E848-0549 available by request