E848-1489 Screening compound: N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide

E848-1489 Screening compound: N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide
E848-1489 Screening compound: N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E848-1489
N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E848-1489

Molecular Formula

C26H33N3O4S (C26 H33 N3 O4 S)

Compound Name

N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide

IUPAC name

N-[2-(2-methoxyphenyl)ethyl]-3-{5-[(4-methylpiperidin-1-yl)sulfonyl]-1H-indol-1-yl}propanamide

SMILES

CC(CC1)CCN1S(c(cc1)cc2c1n(CCC(NCCc(cccc1)c1OC)=O)cc2)(=O)=O

InChI

InChI=1S/C26H33N3O4S/c1-20-10-17-29(18-11-20)34(31,32)23-7-8-24-22(19-23)12-15-28(24)16-13-26(30)27-14-9-21-5-3-4-6-25(21)33-2/h3-8,12,15,19-20H,9-11,13-14,16-18H2,1-2H3,(H,27,30)

InChI Key

FIZNMBQIUJGWCY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14921344

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.63

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.000

Distribution Coefficient, logD

4.000

Water Solubility, LogSw

-4.05

Polar Surface Area

65.710

Acid Dissociation Constant (pKa)

13.91

Base Dissociation Constant (pKb)

4.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

E848-1489 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Lipid Metabolism Library (9174 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with E848-1489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E848-1489?
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What is the minimum amount of E848-1489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E848-1489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E848-1489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E848-1489 available by request